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KMID : 0371319920430040473
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Journal of the Korean Surgical Society
1992 Volume.43 No. 4 p.473 ~ p.482
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The Past and the Present of the Korean Surgical Society
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Abstract
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The accurate and early recognition of the presence of intestinal strangulation in patients with mechanical small bowel obstruction is important to allow safe nonoperative management of selected patients. Traditionally, such recognition is based
on
the
presence of one or more of the classic signs of strangulation obstruction such as continuous abdominal pain, fever, tachycardia, signs of peritoneal irritation, and leucocytosis. Unfortunately, retrospective studies of this problem suggest that
these
individual parameters cannot be relied on for the detection or exclusion of the bowel strangulation.
So there has been many experimental trial to analyse the plasma and peritoneal fluid in order to detect the early stage of bowel strangulation. And the ammonia and lactic acid values in the peritoneal fluid were reported to show confident
increase
in
the strangulation obstruction.
In our experiment we checked lactic acid values in the plasma and peritoneal fluid of the Sprague Dawley rat and the following results were obtained.
1) The plasma lactic acid values in both simple and strangulation obstruction group show no significant changes in 2 and 4 hours after operation.
2) The peritoneal fluid lactic acid values in the simple obstruction group show no significant changes in 2 and 4 hours after operation.
3) The peritoneal fluid lactic acid values in the strangulation obstruction group sow significant increase in 2 hours after operation(p=0.04).
4) The peritoneal lactic acid values increased between 2 and 4 hours after operation but it was relatively insignificant(p=0.07).
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